Optimization and Comparison of Depth-Dose Distribution of Heavy Ion Beam

  • Heavy ion beams used for tumor therapy have some important advantages. Especially, the optimization of the depth-dose distribution of the heavy ion beam in a given focus of a tumor by using a Spread-Out Bragg Peak (SOBP) technique will greatly enhance the therapeutic effects for the tumor therapy. We adopted the simulated annealing algorithm to complete the optimization process for the high energy(-C 120MeV/u) heavy ion beam, which can be supplied by HIRFL, in a 30cm range of water and with 4 different step lengths to give a set of SOBP parameters such as the average dose, the input dose, the ratio of peak to plateau, the standard deviation, etc. The result shows that the selecting of 0.5-1mm as a step length is suitable.
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  • [1] Kraft G. Prog. Part. Nucl. Phys., 2000, 45: 473–5442 Koehler A M et al. Nucl. Instr. and Meth., 1975, 131: 437–440 3 Kanai T et al. Phys., 1983, 10(3) : 344–3464 LI Qiang et al. Nucl. Sci. Techn., 1998, 9(1) : 8–10 5 Castro J R et al. Int. J. Bad. Oncol. Bio. Phys., 1994, 29: 647 6 Boon S N et al. Med. Phys., 1998, 25: 464
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MA Qiu-Feng, JIN Gen-Ming, LI Wen-Jian, LI Qiang and DANG Bing-Rong. Optimization and Comparison of Depth-Dose Distribution of Heavy Ion Beam[J]. Chinese Physics C, 2003, 27(10): 932-935.
MA Qiu-Feng, JIN Gen-Ming, LI Wen-Jian, LI Qiang and DANG Bing-Rong. Optimization and Comparison of Depth-Dose Distribution of Heavy Ion Beam[J]. Chinese Physics C, 2003, 27(10): 932-935. shu
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Received: 2002-11-10
Revised: 1900-01-01
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Optimization and Comparison of Depth-Dose Distribution of Heavy Ion Beam

    Corresponding author: MA Qiu-Feng,
  • Institute of Modern Physics,CAS,Lanzhou 730000,China

Abstract: Heavy ion beams used for tumor therapy have some important advantages. Especially, the optimization of the depth-dose distribution of the heavy ion beam in a given focus of a tumor by using a Spread-Out Bragg Peak (SOBP) technique will greatly enhance the therapeutic effects for the tumor therapy. We adopted the simulated annealing algorithm to complete the optimization process for the high energy(-C 120MeV/u) heavy ion beam, which can be supplied by HIRFL, in a 30cm range of water and with 4 different step lengths to give a set of SOBP parameters such as the average dose, the input dose, the ratio of peak to plateau, the standard deviation, etc. The result shows that the selecting of 0.5-1mm as a step length is suitable.

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