The Manganese Distribution in Olfactory Bulbs of Rat Measured by Synchrotron Radiation X-ray Fluorescence

ZHANG Zhi-Yong; LIU Nian-Qing; LI Fu-Liang; HUANG Yu-Ying; HE Wei; Lei Hao; ZHOU Zhen-You

Chinese Physics C> 2003, Vol. 27> Issue(S1) : 114-117

The Manganese Distribution in Olfactory Bulbs of Rat Measured by Synchrotron Radiation X-ray Fluorescence

Institute of High Energy Physics,CAS,Beijing 100039,China2 Wuhan Institutes of Physics and Mathematics,CAS,Wuhan 430071,China3 Department of Physics,Zhejiang University,Hangzhou 310027,China

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Abstract：
Mn²⁺-enhanced magnetic resonance imaging is very useful for mapping the olfactory bulb,but has poor positional resolution(～100μm)and difficulty with the quantitative analysis of Mn.Synchrotron Radiation X-ray Fluorescence(beam size ～20μm,detect on limit of Mn ～10^－11g) and Energy Disperse X-ray Fluorescence combined with multi-variable statistics were employed to investigate the positional distribution of manganese and other elements in slices of the olfactory bulk of SD rats.The naris of rats were pipetted with MnCl₂ (Mn group n=4) compared with the control group (n=3).Our results show that the manganese distributions in the slices of both groups were non-homogeneous.The difference in the contents of Mn of rats treated with MnCl₂ is as high as 50 times.Rats treated with MnCl₂ exhibited a strong correlation (0.985,p=0.000) between the positional distribution of Mn and Ca,and the contents of Mn,Ca,Zn and Br of the Mn group were 55%,82%,42% and 72% higher than the control group.

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ZHANG Zhi-Yong, LIU Nian-Qing, LI Fu-Liang, HUANG Yu-Ying, HE Wei, Lei Hao and ZHOU Zhen-You. The Manganese Distribution in Olfactory Bulbs of Rat Measured by Synchrotron Radiation X-ray Fluorescence[J]. Chinese Physics C, 2003, 27(S1): 114-117.

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Received: 2003-11-21
Revised: 1900-01-01

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沈阳化工大学材料科学与工程学院沈阳 110142

The Manganese Distribution in Olfactory Bulbs of Rat Measured by Synchrotron Radiation X-ray Fluorescence

Corresponding author: ZHANG Zhi-Yong,

Institute of High Energy Physics,CAS,Beijing 100039,China2 Wuhan Institutes of Physics and Mathematics,CAS,Wuhan 430071,China3 Department of Physics,Zhejiang University,Hangzhou 310027,China

Received Date: 2003-11-21
Accepted Date: 1900-01-01
Available Online: 2003-01-02

Abstract: Mn²⁺-enhanced magnetic resonance imaging is very useful for mapping the olfactory bulb,but has poor positional resolution(～100μm)and difficulty with the quantitative analysis of Mn.Synchrotron Radiation X-ray Fluorescence(beam size ～20μm,detect on limit of Mn ～10^－11g) and Energy Disperse X-ray Fluorescence combined with multi-variable statistics were employed to investigate the positional distribution of manganese and other elements in slices of the olfactory bulk of SD rats.The naris of rats were pipetted with MnCl₂ (Mn group n=4) compared with the control group (n=3).Our results show that the manganese distributions in the slices of both groups were non-homogeneous.The difference in the contents of Mn of rats treated with MnCl₂ is as high as 50 times.Rats treated with MnCl₂ exhibited a strong correlation (0.985,p=0.000) between the positional distribution of Mn and Ca,and the contents of Mn,Ca,Zn and Br of the Mn group were 55%,82%,42% and 72% higher than the control group.