Measurements of 41Ca in Biological Samples by AMS Using CaF2 Target

  • For determining numbers of 41Ca labeled biological samples, the analytical method of 41Ca/40Ca by Accelerator Mass Spectrometry (AMS) using CaF2 target was developed at the Beijing HI-13 AMS system. 41Ca in the biological samples and 41Ca standard samples were prepared to CaF2 with a more effective chemical separation and purification procedure. In the 41Ca AMS measurement, CaF3 negative ion was extracted from ion resource, 7+ charge state of particles was chosen after carbon foil stripping and accelerated at 8.5MV terminal voltage. 41Ca ions were finally recorded by an 140mbar P10 gas filled multi-anode ionization chamber detector. The results showed that 41Ca and the main isobar, 41K could be clearly identified in the two-dimensional density spectra, and the interference of 41K to 41Ca was eliminated with the very low 41K counting rate. The absolute measured values of 4 standard samples with 41Ca/40Ca in the range of 1.785×10-8—1.750×10-10 were in good linear relationship with the standard values (r2=0.997). After normalized with the 1.785×10-841Ca/40Ca standard, the measured values of S2 and S4 standard samples were in good agreement with the nominal values, however, the measured value of S3 deviated the nominal value largely. The 41Ca/40Ca of the biological blanks were estimated below 8.2×10-13.
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  • [1] . Johnson R R, Berkovits D, Boaretto E et al. Nucl. Instrum.Methods, 1994, B92: 483—4882. Freeman S P H T, Beck B, Bierman J M et al. Nucl. In-strum. Methods, 2000, B172: 930—9333. JIANG Shan, HE Ming, DONG Ke-Jun et al. Nucl. In-strum. Methods, 2004, B223/224: 750—7534. Fink D, Middleton R, Klein J et al. Nucl. Instrum. Meth-ods. Phys. Res., 1990, B47: 79—965. Freeman S P H T, Serfass R E, King J C et al. Nucl. In-strum. Methods. Phys. Res., 1995, B99: 557—5616. DONG Ke-Jun, HE Ming, WU Shao-Yong et al. ChinesePhys. Lett., 2004, 21(1): 51—537. YUE Dong-Fang, DONG Ke-Jun, HE Ming et al. Atom.Energy Sci. and Tech., 2004, 38(3): 271—274(in Chinese)(岳东方,董克君,何明等.原子能科学技术,2004, 38(3):271-274)8. WU Shao-Yong, JIANG Shan, DONG Ke-Jun et al. J.Chin. Mass Spectr. Soc., 2002, 23(4): 248—251(in Chinese)(武绍勇,姜山,董克君等.质谱学报,2002, 23(4): 248-251)
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LI Shi-Hong, JIANG Shan, HE Ming, GUAN Yong-Jing, DONG Ke-Jun, WU Shao-Yong, YUAN Yuan, MI Sheng-Quan, LIU Shu-Tian and YUAN Jian. Measurements of 41Ca in Biological Samples by AMS Using CaF2 Target[J]. Chinese Physics C, 2005, 29(12): 1210-1213.
LI Shi-Hong, JIANG Shan, HE Ming, GUAN Yong-Jing, DONG Ke-Jun, WU Shao-Yong, YUAN Yuan, MI Sheng-Quan, LIU Shu-Tian and YUAN Jian. Measurements of 41Ca in Biological Samples by AMS Using CaF2 Target[J]. Chinese Physics C, 2005, 29(12): 1210-1213. shu
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Received: 2005-03-04
Revised: 1900-01-01
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Measurements of 41Ca in Biological Samples by AMS Using CaF2 Target

    Corresponding author: LI Shi-Hong,
  • Department of Nuclear Physics,Chinese Institute of Atomic Energy,Beijing 102413,China

Abstract: For determining numbers of 41Ca labeled biological samples, the analytical method of 41Ca/40Ca by Accelerator Mass Spectrometry (AMS) using CaF2 target was developed at the Beijing HI-13 AMS system. 41Ca in the biological samples and 41Ca standard samples were prepared to CaF2 with a more effective chemical separation and purification procedure. In the 41Ca AMS measurement, CaF3 negative ion was extracted from ion resource, 7+ charge state of particles was chosen after carbon foil stripping and accelerated at 8.5MV terminal voltage. 41Ca ions were finally recorded by an 140mbar P10 gas filled multi-anode ionization chamber detector. The results showed that 41Ca and the main isobar, 41K could be clearly identified in the two-dimensional density spectra, and the interference of 41K to 41Ca was eliminated with the very low 41K counting rate. The absolute measured values of 4 standard samples with 41Ca/40Ca in the range of 1.785×10-8—1.750×10-10 were in good linear relationship with the standard values (r2=0.997). After normalized with the 1.785×10-841Ca/40Ca standard, the measured values of S2 and S4 standard samples were in good agreement with the nominal values, however, the measured value of S3 deviated the nominal value largely. The 41Ca/40Ca of the biological blanks were estimated below 8.2×10-13.

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