Comparison of linac-based fractionated stereotactic radiotherapy and tomotherapy treatment plans for intra-cranial tumors

Get Citation
Jang Bo, Suk Lee, Sam Ju, Sang Hoon, Juree Kim, Kwang Hwan, Chul Kee, Hyun Do, Rena Lee, Dae Sik, Young Je, Won Seob, Chul Yong and Soo Il. Comparison of linac-based fractionated stereotactic radiotherapy and tomotherapy treatment plans for intra-cranial tumors[J]. Chinese Physics C, 2010, 34(11): 1768-1774. doi: 10.1088/1674-1137/34/11/020
Jang Bo, Suk Lee, Sam Ju, Sang Hoon, Juree Kim, Kwang Hwan, Chul Kee, Hyun Do, Rena Lee, Dae Sik, Young Je, Won Seob, Chul Yong and Soo Il. Comparison of linac-based fractionated stereotactic radiotherapy and tomotherapy treatment plans for intra-cranial tumors[J]. Chinese Physics C, 2010, 34(11): 1768-1774.  doi: 10.1088/1674-1137/34/11/020 shu
Milestone
Received: 2009-11-11
Revised: 2010-03-12
Article Metric

Article Views(2504)
PDF Downloads(537)
Cited by(0)
Policy on re-use
To reuse of subscription content published by CPC, the users need to request permission from CPC, unless the content was published under an Open Access license which automatically permits that type of reuse.
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Email This Article

Title:
Email:

Comparison of linac-based fractionated stereotactic radiotherapy and tomotherapy treatment plans for intra-cranial tumors

    Corresponding author: Suk Lee,

Abstract: This study compares and analyzes stereotactic radiotherapy using tomotherapy and linac-based fractionated stereotactic radiotherapy in the treatment of intra-cranial tumors, according to some cases. In this study, linac-based fractionated stereotactic radiotherapy and tomotherapy treatment were administered to five patients diagnosed with intra-cranial cancer in which the dose of 18—20 Gy was applied on 3—5 separate occasions. The tumor dosing was decided by evaluating the inhomogeneous index (II) and conformity index (CI). Also, the radiation-sensitive tissue was evaluated using low dose factors V1, V2, V3, V4, V5, and V10, as well as the non-irradiation ratio volume (NIV). The values of the II for each prescription dose in the linac-based non-coplanar radiotherapy plan and tomotherapy treatment plan were (0.125±0.113) and (0.090±0.180), respectively, and the values of the CI were (0.899±0.149) and (0.917±0.114), respectively. The low dose areas, V1, V2, V3, V4, V5, and V10, in radiation-sensitive tissues in the linac-based non-coplanar radiotherapy plan fell into the ranges 0.3%—95.6%, 0.1%—87.6%, 0.1%—78.8%, 38.8%—69.9%, 26.6%—65.2%, and 4.2%—39.7%, respectively, and the tomotherapy treatment plan had ranges of 13.6%—100%, 3.5%—100%, 0.4%—94.9%, 0.2%—82.2%, 0.1%—78.5%, and 0.3%—46.3%, respectively. Regarding the NIV for each organ, it is possible to obtain similar values except for the irradiation area of the brain stem. The percentages of NIV10%, NIV20%, and NIV30% for the brain stem in each patient were 15%—99.8%, 33.4%—100%, and 39.8%—100%, respectively, in the fractionated stereotactic treatment plan and 44.2%—96.5%, 77.7%—99.8%, and 87.8%—100%, respectively, in the tomotherapy treatment plan. In order to achieve higher-quality treatment of intra-cranial tumors, treatment plans should be tailored according to the isodose target volume, inhomogeneous index, conformity index, position of the tumor upon fractionated stereotactic radiosurgery, and radiation dosage for radiation-sensitive tissues.

    HTML

Reference (1)

目录

/

DownLoad:  Full-Size Img  PowerPoint
Return
Return