Physical Property Measurement of Therapeutic Carbon Ion Beam in the Shallow-Seated Tumor Therapy Terminal at HIRFL

DAI Zhong-Ying; LI Qiang; YAN Zheng; JIN Xiao-Dong; HU Zheng-Guo; XIAO Guo-Qing

Chinese Physics C> 2006, Vol. 30> Issue(9) : 920-924

Physical Property Measurement of Therapeutic Carbon Ion Beam in the Shallow-Seated Tumor Therapy Terminal at HIRFL

Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China2 Graduate University of Chinese Academy of Sciences, Beijing 100049, China

Abstract
HTML
Reference
Related

PDF

Abstract：
For the first time the physical properties of therapeutic carbon-ion beam supplied by the shallow-seated tumor therapy terminal at the Heavy Ion Research Facility in Lanzhou (HIRFL) are measured. For a 80.55MeV/u ¹²C ion beam delivered to the therapy terminal, the homogeneity of irradiation fields is 73.48%, when the beam intensity varied in the range of 0.001—0.1nA (i.e. 1×10⁶—1×10⁸ particles per second). The stability of the beam intensity within a few minutes is estimated to be 80.87%. The depth-dose distribution of the beam at the isocenter of the therapy facility is measured, and the position of the high-dose Bragg peak is found to be located at the water-equivalent depth of 13.866mm. Based on the relationship between beam energy and Bragg peak position, the corresponding beam energy at the isocenter of the therapy terminal is evaluated to be 71.71MeV/u for the original 80.55MeV/u ¹²C ion beam, which consisted basically with calculation. The readout of the previously-used air-free ionization chamber regarding absorbed dose is calibrated as well in this experiment. The results indicate that the performance of the therapy facility should be optimized further to meet the requirements of clinical trial.

References

[1]

. Kraft G et al. Strahlenlher Onkol, 1990, 166: 1-132. Hishikawa Y, Kagawa K et al. J. Jpn. Soc. Ther. Radiol.Oncol., 2002, 14: 73-773. LI Qiang, WEI Zeng-Quan et al. Nuclear Physics Review,2001, 18(2): 109-115(in Chinese)(李强,卫增泉等.原子核物理评论,2001,18(2):109—115)4. WEN Xiao-Qiong, LI Qiang, LI Wen-Jian et al. NuclearPhysics Review, 2001, 18(3): 177-180(in Chinese)(温小琼，李强，李文建等.原子核物理评论,2001,18(3):177—180)5. Faiz M. The Physics of Radiation Therapy. Philadelphia:Lipincott Williams Wilkins. 2003. 106-1766. LI Qiang, XIE Hong-Mei, LI Wen-Jian et al. NuclearPhysics Review, 2003, 20(1): 48-51(in Chinese)(李强，颉红梅，李文建等.原子核物理评论，2003, 20(1): 48-51)7. XIE Hong-Mei, WEI Zeng-Quan et al. Nuclear Technology,1997, 20: 230-234(in Chinese)(颉红梅，卫增泉等.核技术1997, 20: 230-234) 8. YU Chang-Qing et al. The Base of Proton Radiotherapeu-tic Technology. Beijing: Atomic Energy Press, 1999(in Chinese)(郁长庆等.质子治疗技术基础.北京:原子能出版社，1999)9. LI Qiang, WEI Zeng-Quan, LI Wen-Jian et al. HEP NP,1998, 22(7): 646-650(in Chinese)(李强，卫增泉，李文建等.高能物理与核物理，1998, 22(7):646-650)10. ZHU Kun et al. Nuclear Physics Review, 2003, 20(3):197-200(in Chinese)(朱昆等.原子核物理评论，2003, 20(3): 197-200)11. IAEA. Absorbed dose determination in external beam ra-diotherapy: An international code of practice for dosimetrybased on standards of absorbed dose to water. IAEA Tech-nical Reports Series No 398. Austria: IAEA. 2001: 27-13112. Endo M, Koyama-Ito H, Minohara S et al. J. Jpn. Soc.Ther. Radiol. Oncol., 1996, 8: 231-23813. Sihver L, Schardt D, Kanai T. Jpn. J. Med. Phys., 1998,18: 1-2114. Kanai T, Endo M, Minohara S et al. Int. J. Radiat. Oncol.Biol. Phys., 1999, 44: 201-210

[1]	XIA Jia-Wen , ZHAN Wen-Long , WEI Bao-Wen , YUAN You-Jin , YUAN Ping , QIAO Wei-Min . HIRFL-CSR complex. Chinese Physics C, 2009, 33(9): 804-810. doi: 10.1088/1674-1137/33/9/019
[2]	GUO Zhi-Yu , XU Rong , MING Jian-Chuan , ZOU Yu-Bin , GAO Shu-Li , ZHAO Jie , PENG Shi-Xiang , WU Wen-Zhog , QIAN Feng , SONG Zhi-Zhong , YU Jin-Xiang , YUAN Zhong-Xi , YU Mao-Lin . Measurement Techniques of High-Current Ion Beam Emittance. Chinese Physics C, 2008, 32(S1): 148-150.
[3]	ZHENG Chuan , XIAO Zhi-Gang , XU Hu-Shan , XIAO Guo-Qing , ZHAN Wen-Long , LI Zhan-Kui , DUAN Li-Min , SUN Zhi-Yu , YAO Nan , YUAN Xiao-Hua , ZHANG Xue-Ying , WANG Jian-Song , , , , . Hadron Physics Programs at HIRFL-CSRm: Plan and Status. Chinese Physics C, 2007, 31(12): 1177-1180.
[4]	J.P.Briand . Applications of Highly Ionized Ion Beams (abstract only). Chinese Physics C, 2007, 31(S1): 236-236.
[5]	M.P.Stockli . Measuring and Analyzing Transverse Low-Energy Ion Beam Emittances. Chinese Physics C, 2007, 31(S1): 182-186.
[6]	ZHANG Jin-Quan , SONG Ming-Tao , WEI Bao-Wen . Design of Synchrotron for Hadron Therapy. Chinese Physics C, 2007, 31(12): 1122-1125.
[7]	MAO Li-Jun , YANG Xiao-Dong , XIA Jia-Wen , WEI Bao-Wen . Intrabeam Scattering of Heavy Ions at HIRFL-CSR. Chinese Physics C, 2007, 31(10): 947-951.
[8]	DAI Zhong-Ying , LI Qiang , XIAO Guo-Qing , JIN Xiao-Dong , YAN Zheng . Capability Verification of the Beam Delivery System in the Superficially-Placed Tumor Therapy Terminal at HIRFL. Chinese Physics C, 2007, 31(7): 655-659.
[9]	LI Qiang . Conformal Irradiation to Moving Targets in Heavy Ion Radiotherapy with Raster-Scanning Beam Delivery System: (II) Feasibility Experiments. Chinese Physics C, 2006, 30(9): 925-929.
[10]	LI Qiang . Conformal Irradiation for Moving Targets in Heavy Ion Radiotherapy with Raster-Scanning Beam Delivery System (Ⅰ) Simulations. Chinese Physics C, 2005, 29(10): 1006-1011.
[11]	CHEN Zhi-Qiang , YE Yan-Lin , LI Chen , YANG Yong-Feng , ZHAN Wen-Long , XIAO Guo-Qing , XU Hu-Shan , GUO Zhong-Yan , LI Wen-Fei , JIANG Dong-Xing , WANG Quan-Jin , ZHENG Tao , , , , . Investigation of PET Imaging Experiment and Monte Carlo Simulation for Cancer Therapy Using Heavy-Ion Beams at HIRFL. Chinese Physics C, 2004, 28(7): 792-796.
[12]	MA Qiu-Feng , JIN Gen-Ming , LI Wen-Jian , LI Qiang , DANG Bing-Rong . Optimization and Comparison of Depth-Dose Distribution of Heavy Ion Beam. Chinese Physics C, 2003, 27(10): 932-935.
[13]	LI Qiang , WEI ZengQuan , LI WenJian . Calculation of Depth-Dose Distribution of Intermediate Energy Heavy-Ion Beam. Chinese Physics C, 2000, 24(5): 414-417.
[14]	Tang Jingyu , Lei Wen , Wang Yifang . Beam Loss in HIRFL-CSR Due to CollisionsWith Residual Gas in Vacuum. Chinese Physics C, 1998, 22(8): 745-754.
[15]	Li Qiang , Wei Zengquan , Li Wenjian , Zhou Guangming , Dang Bingrong , Cai Xichen , He Jing , Xie Hongmei , Han Guangwu , Huang Tao , Chen Weiqiang , Wang Jufang , Zhang Shumin . Extending of the Bragg Peak of Heavy lon Beam. Chinese Physics C, 1998, 22(7): 646-650.
[16]	Rao Yinong , Xia Jiawen , Yuan Youjin , Wei Baowen . Electron Beam Transverse Temperatures on Hirfl-CSR E-Cooler. Chinese Physics C, 1996, 20(4): 369-375.
[17]	Li Qingrun , Yang Yongxu . A Study of Carbon Heavy Ion Scattering. Chinese Physics C, 1994, 18(8): 748-751.
[18]	FENG En-Pu , ZHU Yong-Tai , GUO Zhong-Yan , QIAO Wei-Min , ZHAN Wen-Long , SHEN Wen-Qing , WANG Xiao-Qiu , WANG Bing , YIN Shu-Zhi , FENG Jun , LIU Guan-Hua , XI Hong-Fei , FAN En-Jie , ZHU Xiang , ZHOU Jian-Qun , ZENG Yao-Wu . The Experimental Terminal of Large Area Ionization Chamber at HIRFL Accelerator. Chinese Physics C, 1991, 15(5): 442-449.
[19]	YU Qing-Chang . A DISCUSSION OF TRANSFORMATIONS OF STRIP ION BEAMS INTO AXISYMMETRICAL BEAMS. Chinese Physics C, 1989, 13(2): 106-108.
[20]	YU Qing-Chang . THE MUTUAL TRANSFORMATION OF STRIP ION BEAMS AND AXISYMMETRICAL ION BEAMS. Chinese Physics C, 1984, 8(2): 191-198.

Access

Get Citation

DAI Zhong-Ying, LI Qiang, YAN Zheng, JIN Xiao-Dong, HU Zheng-Guo and XIAO Guo-Qing. Physical Property Measurement of Therapeutic Carbon Ion Beam in the Shallow-Seated Tumor Therapy Terminal at HIRFL[J]. Chinese Physics C, 2006, 30(9): 920-924.

RIS(for EndNote,Reference Manager,ProCite)

BibTex

Txt

Milestone

Received: 2005-11-28
Revised: 2006-01-20

Article Metric

Article Views(4497)
PDF Downloads(678)
Cited by(0)

Policy on re-use

To reuse of subscription content published by CPC, the users need to request permission from CPC, unless the content was published under an Open Access license which automatically permits that type of reuse.

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Physical Property Measurement of Therapeutic Carbon Ion Beam in the Shallow-Seated Tumor Therapy Terminal at HIRFL

Corresponding author: LI Qiang,

Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000, China2 Graduate University of Chinese Academy of Sciences, Beijing 100049, China

Received Date: 2005-11-28

Accepted Date: 2006-01-20

Available Online: 2006-09-05

Abstract: For the first time the physical properties of therapeutic carbon-ion beam supplied by the shallow-seated tumor therapy terminal at the Heavy Ion Research Facility in Lanzhou (HIRFL) are measured. For a 80.55MeV/u ¹²C ion beam delivered to the therapy terminal, the homogeneity of irradiation fields is 73.48%, when the beam intensity varied in the range of 0.001—0.1nA (i.e. 1×10⁶—1×10⁸ particles per second). The stability of the beam intensity within a few minutes is estimated to be 80.87%. The depth-dose distribution of the beam at the isocenter of the therapy facility is measured, and the position of the high-dose Bragg peak is found to be located at the water-equivalent depth of 13.866mm. Based on the relationship between beam energy and Bragg peak position, the corresponding beam energy at the isocenter of the therapy terminal is evaluated to be 71.71MeV/u for the original 80.55MeV/u ¹²C ion beam, which consisted basically with calculation. The readout of the previously-used air-free ionization chamber regarding absorbed dose is calibrated as well in this experiment. The results indicate that the performance of the therapy facility should be optimized further to meet the requirements of clinical trial.

HTML

Reference (1)

Physical Property Measurement of Therapeutic Carbon Ion Beam in the Shallow-Seated Tumor Therapy Terminal at HIRFL

Abstract：

References

Access

Article Metrics

Metrics

通讯作者: 陈斌, bchen63@163.com

Email This Article